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MEMBERSHIP  ::  Meet the Microbiologist

Meet the Microbiologist

Understanding the Role of Mycobacterium bovis (M. bovis) Cell Wall Antigens in Bovine Tuberculosis Pathogenesis

Bovine tuberculosis caused by M. bovis results in major financial losses to the cattle industry and also poses a serious health risk to people in many countries. Vaccines are invaluable medicines that help prevent infections. Despite the urgent need, there is no licensed vaccine available to prevent bovine tuberculosis.To develop an effective vaccine, an understanding of the pathogenesis of bovine tuberculosis is important and specifically, how certain biomolecular products released by M. bovis interact with the host immune system. Ongoing research by our team focused on assessing theimmunogenicity of three different classes of M. bovis biomolecular signatures - proteins, cell wall lipids and cell surface sugars on bovine dendritic cells, which are immune cells key to controlling TB.In the long-term, these studies will contribute to our understanding of bovine TB pathogenesis and may benefit efforts to develop effective vaccine for this devastating disease.  

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Olivia Ihedioha

Olivia Ihedioha is a PhD student at Western College of Veterinary Medicine (WCVM),Vaccine and Infectious Disease Organization-International Vaccine Centre (VIDO-InterVac), University of Saskatchewan. She is working with tuberculosis (TB) research team at VIDO-InterVac led by Drs. Andrew Potter and Jeffrey Chen. Research interest focused on understanding the pathogenesis of bovine tuberculosis and vaccine development.

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Contact Information
University of Saskatchewan
VIDO InterVac, 120 Veterinary Road
Saskatoon,  S7N 5E3

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