The Department of Microbiology offers graduate programs leading to the M.Sc. and Ph.D. degrees. All aspects of the Graduate Program in Microbiology are administered and monitored by the departmental Graduate Affairs Committee (GAC), chaired by a faculty member appointed by the Head of Microbiology. The Department has expertise necessary for the instruction and training of advanced students in areas that include cellular and molecular biology of eukaryotes, microbial genetics and molecular biology, immunology, medical microbiology, medical virology, microbial physiology, and molecular virology of eukaryotes. Students are generally admitted for advanced study and specialization in one of these seven subspecialties.
The Royal University Hospital’s Department of Clinical Microbiology is an integral part of the Department of Microbiology, providing diagnostic services in bacteriology, virology, mycobacteriology, mycology, parisitology and immunology. The Saskatoon Cancer centre serves as the centre for cancer research for the University of Saskatchewan.
List of Faculty
Dr. J. Blondeau - Laboratory diagnosis of infectious diseases in clinical microbiology; molecular basis of antimicrobial resistance; patterns in antimicrobial resistance, antimicrobial synergy, reversion time MIC's, ongoing research projects.
Dr. P. Bretscher - Mechanisms responsible for self-nonself discrimination and immune class determination. Immune responses in autoimmunity, to tumours, and in chronic infectious diseases, and strategies of vaccination.
Dr. H. Bull - Homologous recombination, adaptive mutation, DNA replication.
Dr. S. A. Carlsen - Tumor metastasis with special emphasis on the tumor cell surface, cellular interactions and the role of hydrolytic enzymes in tumor invasion and metastasis.
Dr. J.R. Dillon - Proteins implicated in bacterial cell division, using round bacteria as model organisms; Antimicrobial surveillance, antibiotic resistance mechanisms and molecular epidemiology of bacterial isolates, with emphasis on the human pathogen Neisseria gonorrhoeae; Antimicrobial activities of natural products.
Dr. H. Goldie - Genetic regulation of the pckA gene in Escherichia coli. Structure and regulation of phosphoenolpyruvate carboxykinase in E. coli. Regulatory roles of calcium in bacteria.
Dr. C. Havele - Quantitative and qualitative analysis of the cellular and molecular interactions leading to the activation and differentiation of distinct T cell subsets.
Dr. S. Hayes - Bacteriophage genetics: regulation of chromosomal rearrangements, mutagenic mechanism, developmental regulation immunity/exclusion, replication initiation.
Dr. S. Hemmingsen - Cell cycle regulation. Cytoskeletal protein structure and function. Molecular chaperone structure and function. Phage antibody display technology.
Dr. S. P. Howard - Molecular biology of toxin secretion by Gram-negative bacteria. Structure, function and biogenesis of the outer membrane.
Dr. K. McClean - Major interests are in the areas of clinical infectious diseases and medical education. Sero-prevalence studies of blood borne pathogens in Zambia and antimicrobial susceptibility of respiratory pathogens in Zambia. Needlestick injuries - financial and psychosocial costs.
Dr. V. Misra - Elucidating the molecular mechanisms by which herpesvirus cause infections and disease.
Dr. D. Quest - Immunology/Virology related research interests: Pharmacological manipulation of the TH1/TH2 nature of immune response. Clinical: antiviral regimens (optimize pharmacokinetics).
Dr. K. E. Williams - Major interests are in the genus Serratia, pathogenesis and immunology of infections in the immune-compromised patient, outer membrane proteins of gram negative organisms, mechanisms of resistance to heavy metals and immunodiagnostic/immunotherapeutic approaches to bacterial infections. Actively involved in clinical research including antibacterial and antiviral treatment trials as well as HIV epidemiology and drug trials.
Dr. P. Willson - Vaccine design and testing for bacterial pneumonia in swine. Epidemiology, immunology and pathogenesis related to infectious diseases in livestock.
Dr. J. Xiang - Molecular tumor immunology. The study of (i) distinct roles of dendritic cell and T cell subsets and dendritic and T cell communications in antitumor immune responses and (ii) the development of engineered T cells, engineered dendritic cell vaccine and gene therapy in combating well-established tumors.
Dr. W. Xiao - Molecular mechanisms of DNA alkylation damage and repair. Mechanisms of gene regulation in response to DNA damage. Chemical mutagenesis and carcinogenesis.
Financial Support Available
Financial assistance at the M.Sc. or Ph.D. level is coordinated through the Graduate Affairs committee of the Department.
The Student Financial Assistance & Awards office includes government loan program advocacy, emergency loan assistance and scholarship and bursary programs. This office provides:
- government loan advocacy with regard to reassessments, appeals, exceptional circumstances, and other financial assistance issues.
- short-term, interest free loans to students who are experiencing temporary unexpected financial expenses, and who do not have access to any other sources of funding.
- provision of scholarships and bursaries; eligibility criteria can include academic achievement, financial need and contributions to school and community life
Admissions and EnquiriesGraduate Chair Dr. Peter Bretscher
Department of Microbiology and Immunology
College of Medicine
University of Saskatchewan
Saskatoon, Saskatchewan S7N 5E5