Studying Microbiology in Canada
|University of Manitoba
The Department of Medical Microbiology offers programs of studies leading to the M.Sc. and Ph.D. degrees with research and academic experience suitable for a career in basic microbiology or infectious diseases.
The Department has nationally recognized strengths in several areas, particularly epidemiology. It also enjoys extensive collaborative projects with both the University of Kenya in Nairobi, Kenya, and with the new federal laboratories for disease research. The Nairobi project uses epidemiologic, biologic, and molecular biologic studies to better understand sexually-transmitted diseases in the African population. Numerous opportunities for collaborative work with members of other departments as well as with various affiliated research organizations (including the Clinical Microbiology Laboratories of the Health Sciences Centre, the Infectious Diseases programs of the Health Sciences Centre, the Cadham Provincial Laboratory, the federal laboratories, and St. Boniface Hospital) exist.
Recent graduates of the program have been highly successful in academia, industrial, medical, and veterinary careers
Scientific interests of the faculty include: gene regulation, molecular basis of cellular functions to the development of vaccines and diagnostics for human health and veterinary diseases, cell and molecular biology, immunology, virology, bacterial genetics, microbial pathogenicity, Chlamydial biology, and clinical microbiology. Many research projects are oriented to human diseases and many are carried out in collaboration with physicians who have access to patients.
- Confocal and Image Analysis Facility which houses the Fluoview confocal microscope, a state-of-the-art research tool which allows researchers to visualize the molecular architecture of cells and tissues.
- Electron Microscopy unit which utilizes a Philips model 201 transmission electron microscope, which is capable of visualizing the results from most routine and experimental methods of electron microscopy. Sectioning is performed with an LKB Ultratome III with either diamond or glass knives, and all photography is conducted in the lab using Kodak chemistry. A Beckman Airfuge is also available for the preparation of suspension samples.
- Flow Cytometry Facility (FACS) which operates two instruments: A Becton Dickenson FACS Calibur, equipped with 488 nm Argon-ion and red diode lasers for four colour analysis with cell sorting capabilities (300 cells / second) that is best for cell enrichment of populations with frequencies over 10%. Data acquisition and analysis is through Cell Quest Pro software. For maximum efficiency, a second analysis workstation complete with the Cell Quest Pro software, is available. The second instrument is a Beckman Coulter Epics Elite, two laser, four colour, high-speed sorter (5,000 cells / second). This instrument is located in our biosafety level 3 laboratory allowing sorting of viable human cells from normal controls and those exposed or infected with class III - non-aerosol pathogens (such as HIV). This instrument is idea of analyses requiring live human cells (apoptosis assays) and sorting of rare cell types for cloning or further analysis.
- Genetic Analysis Core operates a Roche LightCycler and a ABI 310 single capillary genetic analyse and an ABI 3100 16 capillary genetic analyser.
- Viral Immunology Core - The Core is equipped with four six-foot Biological Safety Cabinets, six CO2 incubators, a Packard cell harvester, a Packard Topcount 96 well scintillation and luminescence detector, a Molecular Devices Spectramax UV spectrophotometer/ELISA reader, an Eppendorf Mastercycler gradient thermal cycler, an MVE 1520 HE 33,000 sample liquid nitrogen storage facility, an ELISpot reader, and a Nikon inverted fluorescent/phase contrast microscope with digital camera. The lab is networked to a server so that data can be easily and safely exported out of the laboratory.
List of Faculty
Alfa, Michelle - Nosocomial infections including Clostridum difficile associated diarrhea and infection transmission due to medical device biofilm build-up.
Andonov, Anton - Molecular biology, epidemiology, diagnostics and prevention (edible vaccines) of human hepatitis (A,B,C,D,E) and other bloodborne viruses (HGV,TTV,TLMV).
Aoki, Fred Y. - Antiviral chemotherapy of herpes simplex virus, HIV and Influenza A virus infection
Artsob, Harvey - Surveillance for, and characterization of, zoonotic disease agents in Canada; development of diagnostic tests to detect these agents
Bernard, Kathryn - Systematics of non-enteric bacterial pathogens; characterization and development of laboratory response to bacterial agents of bioterrorism.
Berry, Jody - Immunogenetics of antibody responses to infectious agents.
Blanchard, James - Epidemiology of infectious diseases.
Booth, Stephanie - Genomic and proteomic approaches for the identification of biomarkers in prion diseases, the signal transduction pathways leading to neurodegeneration in prion diseases, the role of exosomes in prion pathobiology and transmission.
Booth, Timothy - Virus structure and morphogenesis. Biological transmission by arthropod vectors. Diagnosis and pathology of animal viruses.
Bow, Eric J. - The prevention and management of bacterial and fungal infections in neutropenic cancer patients, the impact of cytotoxic therapy-induced intestinal epithelial damage on the pathogenesis of invasive infection in cancer patients; and the impact of cytotoxic therapy upon quality of life in cancer patients.
Butler-Jones, David - Population and public health, organizational delivery of health services, determinants of health.
Cao, Jingxin - Hepatitis B and C immunopathogenesis, with particular interests in those viral proteins with potential immuno- regulatory functions; development of novel therapeutic vaccines for chronic viral infections.
Carpenter, Michael - Molecular mechanism of Hepatitis C virus replication and cellular pathogenesis. Host cell regulators of viral gene expression
Clark, Clifford - Virulence factors, including protein exotoxins, of E. coli, Salmonella, Aeromonas and Campylobacter species.
Coombs, Kevin M. - Determining molecular signals involved in the structure / function, assembly, and pathogenesis of viruses and the diseases they cause.
Czub, Markus - Pathogenesis studies on virus infections.
Dawood, Magdy R. - HIV detection, the role of the immune system in protection against HIV infection.
Drebot, Michael - Molecular diagnostics and genetic characterization of emerging viral and bacterial zoonotic pathogens such as hantaviruses, arboviruses, and tick-borne pathogens.
Elliott, Lawrence J - Epidemiology of communicable diseases, including sexually-transmitted infections and tuberculosis.
Embil, John - Infectious disease consultant whose research focuses on nosocomial infections, their prevention, transmission and epidemiology.
Embree, Joanne E. - Perinatal infections: Effect on prematurity, pregnancy and neonatal complications. STDs in Pediatric. Pediatric AIDS.
Fast, Margaret - Epidemiology of communicable diseases
Feldmann, Heinrich - Researching emerging/re-emerging biosafety level (BSL) 3 and 4 viruses.
Ferguson, Alan - A social scientist with research interests in reproductive health, particularly the socio- demographic aspects of HIV/AIDS and family planning in sub-Sahara Africa and the development of elicitation methods in these fields.
Fowke, Keith - Immunobiology of HIV infection
Gelmon, Lawrence - AIDS/STD training and capacity-building in Eastern and Southern Africa. Tropical public health and international development.
Gilmour, Matthew - The burden of illness due to microbial pathogens is often represented by well-characterized pathogens (such as Escherichia coli O157:H7 causing ‘Hamburger disease’), whereas the true extent of microbial species which are human pathogens is much more diverse.
Gin, Alfred - Antibiotic resistance, antimicrobial drug use evaluation, antimicrobial cost containment.
Hammond, Gregory W.- Study of the dynamics of communicable diseases and various public health issues for the population of Manitoba
Harding, Godfrey K.M. - Pathogenesis and prevention including vaccine efficacy in women with recurrent UTI's.
HayGlass, Kent - The immunoregulatory role of Th1 vs Th2 cytokine production in determining the balance between hypersensitivity, protective immunity and unresponsiveness.
He, Runtao - Molecular virology and cell biology. Research projects focus on molecular pathogeneses of SARS coronavirus and hepatitis C virus.
Hoban, Daryl - Molecular basis of antibiotic action. Surveillance of resistant pathogens
Jackson, Michael - The development and application of advanced in vivo imaging (MRI, fluorescence etc) and spectroscopic (infrared, Raman etc) techniques to study infectious diseases.
Jay, Francis T. - Mechanisms of the antiviral and antitumour activities of interferons. Structure-function studies of interferons by gene modification and monoclonal antibody analysis.
Johnson, Wendy - molecular diagnostics and epidemiology; bacterial pathogenesis and virulence mechanisms; antibody-based therapeutics; recombinant therapeutic proteins Cangene Corporation
Kabani, Amin - Molecular diagnostics, antimicrobial resistance
Karlowsky, James - Antimicrobial susceptibility testing methods; and the development and implementation of molecular diagnostic methods for pathogen identification, epidemiological typing and tracing, and antimicrobial resistance detection in clinical microbiology laboratories.
Kasper, Ken - Medical education: HIV
Joshua Kimani - Epidemiology and Immunobiology of STIs, Mechanisms of HIV resistance among highly exposed Kenyan sex workers, health services research especially integrated programs and the role of Microbicides and pre-exposure prophylaxis in HIV control.
Klonisch, Thomas - Determining molecular signalling, structure/function relationships and proteomic changes mediated by the actions of membrane-anchored proEpidermal Growth Factor (EGF) family members and the relaxin hormone in tumor cells.
Knox, David - Prion or transmissible spongiform encephalopathy (TSE) diseases.
Kobinger, Gary - My main interest is to develop and test novel vaccine platforms for different applications including the protection against emerging pathogens.
Krause, Denis - Molecular microbial ecology of the human gut as it relates to inflammatory bowel disease, antibiotic resistance determinants, and survival and persistence of pathogens
Kumar, Anand - Sepsis and septic shock as it relates to cardiovascular dysfunction and response to antimicrobial therapy.
Li, Yan - Molecular biology and genetics of respiratory viruses such as influenza, RSV, and parainfluenza virus.
Lo, Evelyn - Nosocomial infections: epidemiology, prevention and transmission, quality improvement in reducing ventilator associated pneumonia. Infectious Diseases
Mburu, David N. - Population genetics of microbial pathogens and their host.
McClarty, Grant A. - Biochemical studies on the cell-cell interactions that occur between the obligate intracellular bacterial pathogen Chlamydia and the host cell.
Milley, Douglas - Molecular diagnostics in virology.
Morris, Chester - Targeted HIV interventions in vulnerable groups, impact assessment of HIV in Africa and models of HIV service delivery in the private sector in resource limited settings.
Moses, Stephen - Epidemiology and control of communicable diseases, with particular emphasis on STDs and HIV infection.
Mulvey, Michael - Research interstes include bacterial pathogenesis and novel antimicrobial resistance mechanisms.
Nagelkerke, Nico - Biostatistics and epidemiology with a focus on the methodology of infectious disease research.
Niazi, Wassay - Stop Afghan Aids
Nicolle, Lindsay E. - Urinary tract infection, hospital acquired infections, antimicrobial resistance, infections in long term care facilities
Noreddin, Ayman - Pharmacokinetics/Pharmacodynamics of antimicrobials, population pharmacokinetics, Monte Carlo analysis and clinical simulations.
Orr, Pamela H. - Epidemiology of Chlamydia trachomatis and tuberculosis epidemiology of infections in the elderly and aboriginal populations.
Osiowy, Carla - Molecular characterization of Hepatitis B virus (HBV): investigation of drug-resistant and vaccine-escape mutants; molecular evolution studies.
Parker, Jim -
Peeling, Rosanna - Epidemiology, pathogenesis and diagnosis of sexually transmitted diseases; reproductive health World Health Organization
Plourde, Pierre - Risks to Canadians travelling to foreign destinations. Assessment of immigrants and refugees from developing countries. Epidemiology of social sexual and IDU networks. Epidemiology of enteric pathogens
Plummer, Francis A. - Ecology and epidemiology of Neisseria gonorrheae. Immune response to N. gonorrheae. Transmission dynamics of HIV-1 in Africa. National history of HIV-1 in Africa. Perinatal transmission of HIV-1 in Africa (University of Nairobi)
Ronald, Allan R. - ARV delivery and education in developing countries,
Rubinstein, Ethan -Antibiotic resistance in B. anthracis and other organisms of bio-terrorism; Effect of antibiotics on toxins production by bacteria; Community-acquired methicillin-resistant staphylococcus aureus infection in indigenous populations; Pharmacodynamic models for assessing antibiotic efficacy
Severini, Alberto - Genomics of herpesviruses. Herpesvirus replication and pathogenesis mechanisms. Human papillomavirus testing and molecular epidemiology.
Sharma, Meenu - Mycobacterial pathogenicity with special interest in mycobacterial cell wall and host-immune response interaction.
Tipples, Graham - Diagnostics, surveillance and research on viruses causing rash illnesses in humans including measles virus, rubella virus and herpesviruses.
Van Caeseele, Paul
Wagener, Stefan - Survival and inactivation of infectious agents on environmental surfaces. Assessing personal protective equipment, engineering controls and chemical agents in their ability to control biohazards.
Wang, Gehua - Molecular biology and pathogenesis of enterobacteria; identification and characterization of Campylobacter virulence factor
Weingartl, Hana - Emerging diseases, zoonotic viruses of veterinary importance, pathogenesis, virus-host interaction, animal models
Wylie, John - Molecular epidemiology of sexually transmitted and blood-borne pathogens within human social and sexual networks. Population genetics of pathogenic bacteria. DNA-based microbial typing and detection methods
Yang, Xi - Role of cytokines in the regulation of protective immunity to, and pathogenesis of intracellular bacterial infection
Yao, Xiao-Jian - Molecular mechanisms underlying HIV-1 replication, dissemination and pathogenesis, and to develop effective preventative, and therapeutic strategies against the spread of HIV-1 infection.
Zhanel, George - Epidemiology of and mechanism of antimicrobial resistance. Pharmacodynamics of antimicrobials
Zhong, Wen - Transport behaviour of fibrous/biomedical materials; Protection and defense textiles against microorganisms; Skin/fabric interactions and related contact dermatitis; Fiber reinforced polymer composites.
Financial Support Available
The Department of Medical Microbiology currently has a limited number of graduate stipends which it can award to faculty members to support students. Applications for these stipends are made by the supervisor to the GSC using the Student Stipend Application Form. The value of the awards is adjusted from time to time.
There are several other ways to finance graduate studies at The University of Manitoba:
- External granting agency fellowships - NSERC, SSHRC, CIHR and MHRC have a value in excess of $16,000/yr. Normally the deadlines for these competitions are prior to December of the academic year preceding the year when funding begins. Applicants must be Canadian citizens or permanent residents to be eligible for these awards.
- Dean of Graduate Studies Student Achievement Award.
- University of Manitoba Graduate Fellowships (UMGF)
- Faculty/Departmental Bursary/Scholarship/Award
- Research and Teaching Assistantship opportunities
- Canadian federal, provincial and territorial government loans/bursaries
Admissions and Enquiries
Department of Medical Microbiology
510 Basic Medical Sciences Building
University of Manitoba
730 William Avenue
Winnipeg, Manitoba R3E 0J7
The Faculty of Graduate Studies
500 University Centre, University of Manitoba
Winnipeg, Manitoba R3T 2N2