Studying Microbiology in Canada
Pathology & Molecular Medicine
The Faculty of Health Sciences offers Graduate programs in various areas of the Health Sciences. The Department of Pathology and Molecular Medicine is involved in the Medical Sciences Graduate Program, along with other departments in the faculty. An interdisciplinary approach to learning is emphasized in all of the Faculty of Health Sciences Graduate Program.
The division of Clinical Pathology encompasses the disciplines of hematology, genetics, microbiology, clinical chemistry, immunology and histocompatability. Similar to anatomic pathology, the primary mandate of this division is to provide clinical services to hospitals in the Hamilton region, facilitated through the Hamilton Regional Laboratory Medicine Program (HRLMP).
The research laboratories in the Health Sciences Centre at McMaster are well-supported and augmented by those in associated institutions located in Hamilton, e.g. the Hamilton Civic Hospitals Research Centre, the Father Sean O'Sullivan Research Centre and the Hamilton Regional Cancer Centre.
A number of well-equipped on-campus facilities are available for use including the:
- Central facility of the Institute for Molecular Biology which provides important services to faculty using molecular biological techniques, including oligonucleotide and peptide synthesis and automated DNA sequencing
- Central Animal Facility
- Central Analytical Facility
- Occupational & Environmental Health Laboratory
- Electron Microscope (and Confocal Light Microscope) Facility
- Computer Services Unit.
- Health Sciences Library
List of Faculty
Alexopoulou, Iakovina - Autopsy and Renal Pathology
Alowami, Salem - Clinical (translational) research in skin and breast cancer.
ASHKAR, Ali A. - Innate Immunity, NK/NKT cells, IL-15, Mucosal Immunity, Toll-like Receptors, dsRNA, Tumor, Stem Cell Transplantation
Austin, Richard - Molecular biology of vascular disease and thrombosis
Balion, Cynthia – Clinical Chemistry
BIENENSTOCK, John - Mast Cells, Neuro-Immune, Mucosal Immunity, Probiotics, Behaviour
Blajchman, Morris - Transfusion Medicine and hemostasis
Bourgeois, Jacqueline – Pediatric pathology
Boutross-Tadross, Odette - Gynaecological and Breast pathology
BRAMSON, Jonathan - T lymphocyte, Genetic Vaccine, Gene Therapy, Virus, Cancer, Flow Cytometry
Brook, Michael - Silicone chemistry, stabilizing enzymes in silicones and silica, passivating biomaterials
Buchanan, Michael - Monohydroxide regulation of blood and vascular wall cell adhesivity, and it's relationships to actue thrombus formation and chronic intimal hyperplasia. Oral monohydroside therapy and the treatment, prevention and regression of vascular hyperplasia.
Butler, Richard - plasticity of highly differentiated cells in adult mammals.
Carter, Ronald – Medical Genetics; Cancer Genetics
Chen, Vicky - Diagnostic Cytopathology, Head and Neck Pathology and Hematopathology
CHERNESKY, Max A. - Rapid Diagnosis, Infections, Immunization, Methods, Mechanisms, Pathogenesis, Laboratory
Chetty, Tony - Metabolic Syndrome, diabetes Prevention, Lipid Metabolism and Obesity.
Chorneyko, Katherine – Diagnostic electron microscopy and its clinical applications in platelet dysfunction, renal glomerular diseases, muscle disorders, neoplastic and metabolic processes; Renal Pathology; General Surgical Pathology and Cytology.
CLARK, David A. - Pregnancy Immunology, Tolerance, Cytokines, Transfusion immunomodulation, CD200, fgl2
Coyle, Anthony - T cell costimulation and activation.
Daya, Dean - gynecologic and urologic pathology
DeNardi, Franco - Clinical gastrointestinal disease and interstitial laser photocoagulation.
Deodhare, Sanjeev -Hematopathology
Doering, Laurie - Stem Cells, Neural Transplantation and CNS Disorders.
Dolling, Jo-Anna - Molecular Genetics and Cytogenetics
Evelegh, Michael - Development of diagnostic tests for the early detection of cardiovascular disease and cancer; Defining the relationship between cholesterol in the skin and cardiovascular disease risk; Development of novel technologies applicable to in vitro diagnostics
Fernandes, John – Forensic pathology; the impact of ‘club’ drugs; Gunshot injury; Perinatal and placental pathology; Pathology of high risk obstetrics; Evidence based practice of medicine; Impact of decreased length of stay on the outcome of clinical care; Impact of decreased length of stay on the outcome of clinical care; Impact of health sector economic distribution on clinical outcomes; Evaluation of community based teaching.
Fletch, Andrew – Spontaneously occurring rat models of dysmelination; Analgesics and pain management; Infectious diseases caused by viral protozoan agents
FOLEY, Ronan S. - Gene Transfer, Dendritic Cells, Adenoviral Gene Transfer, Cytokines, Stem Cells, Clinical Trials
Freeman, Viola – Rapid chromosome diagnosis; Association of radiation exposure and abnormal chromosome segregation; Twinning in spontaneous abortions; Non-disjunction in Down syndrome; Neoplasia
GAULDIE, Jack - Cytokine and Dendritic Cells, Inflammation and Immunity, Fibrosis, Tumour Immunotherapy, Interleukin-6, Gene Therapy
Grey, Vijaylaxmi - Determinants of bone health in Cystic Fibrosis
Gohla, Gabriella - Breast pathology; Skin pathology
Groves, David - Development, implementation and assessment of new diagnostic technologies, including molecular diagnostic tests
Groves, Hallie – The effect of different strategies to stimulate and link the learning of anatomy in problem-based learning programs; the computer capture and processing of digital images of anatomical material for use in the development of educational resources; The determination of the factors that cause stress of anxiety in students working in an anatomy lab, and strategies for modifying these factors; the use of ultrasound in the anatomy lab for teaching ‘living anatomy’
HARNISH, Delsworth G. - HPV, Molecular Biology, Education
Haslam, Richard - Signal transduction pathways involved in the regulation of blood platelet function
Hill, Stephen – Markers of cardiac injury and outcome prediction in Acute Coronary Syndrome; Homocysteine and vascular disease; Apolipoprotein E
Hitt, Mary - Development of Adenovirus Vectors for the Gene Therapy of Cancer
Hortelano, Gonzalo – Gene therapy
Horsewood, Peter – Development of non-invasive diagnostic assays; Production and characterization of monoclonal antibodies; Development of immunoassay and immunodiagnostic methods; Immunochemical methods of analysis; Mechanisms of thrombocytopenias and the role of specific platelet molecules in hemostasis; Mechanisms of platelet activiation; Transfusion medicine procedures; risk factors in atherosclerosis; Detection of cancer markers
Igdoura, Suleiman - Molecular genetics of sialidase and its role in monogenic as well as multifactorial diseases
Jayaratne, Padman – Microbial source tracking, Microbial Pathogenesis, Molecular diagnostics, Environmental gene pool, Antibiotic resistance.
Jones, Kim - Interactions between tissue engineering and the host response
JORDANA, Manel - Allergic Inflammation, Asthma, Peanut-induced Anaphylaxis, Immune Regulation, Cytokines, Chemokines, Co-stimulatory Molecule
Kapusta, Linda - prostate carcinomas.
Karmali, Mohamed - Epidemiology, pathogenesis, and public health significance of emerging zoonotic enteric pathogens
KAUSHIC, Charu - Mucosal Immunology, Female Genital Tract, Sexually Transmitted Diseases, Sex Hormones, HIV, Vaccines
Kay, Michael - Pulmonary pathology, pulmonary vascular disease, pulmonary hypertension, drug-induced lung disease.
Kelton, John - Investigating the immune mechanisms in various clinical platelet disorders
KOLB, Martin - Lung Fibrosis,Tissue Repair, GeneTherapy, Small Animal Imaging, Drug Trials, Clinical Research
Lach, B - Pathology and immunohistochemistry of human Herpes Simplex Encephalitis and other viral infections of the CNS; Mitochondrial encephalomyopathies; Pathology, biochemistry and tissue culture studies; Muscle pathology in Leber's optic atrophy - tissue culture, mitochondrial DNA and ultrastructudy; Neurooncology
Lee, Christine - Optimal laboratory methods of diagnosis and treatment of Clostridium difficile--associated diarrhea; refining microbiologic diagnosis of sexually transmitted diseases; and, diagnosis and management of nosocomial infections (intravenous catheter infections, ventilator-associated pneumonia
Lee, Jonathan - Apoptosis and the regulation of mitosis
LICHTY, Brian - Vesicular Stomatitis Virus, Coronavirus, Cancer, Myeloma, Interferon
Loeb, Mark - Emerging infectious diseases, infections in seniors, influenza and other respiratory infections, and antimicrobial use and resistance
Marci, Joseph - Investigating the mechanisms involved with regulating the assembly and secretion of hepatic lipoproteins; Utilizing proteomics-based technologies to investigate specific cellular and intracellular mechanism associated with the development of atherosclerosis.
MAHONY, James B. - Infectious Diseases, Chlamydia Pneumoniae, Virology, Atherosclerosis, Pathophysiology, Gene Expression, SARS, West Nile Virus
Main, Cheryl – Sexually Transmitted Infections; Electronic Educational Learning Tools; Laboratory Safety
MARGETTS, Peter J. - Adenovirus, Fibrosis, Angiogenesis, Gene Therapy, Laser Capture Microdissection, Gene Regulation, Renal Disease, Peritoneal Dialysis
McDERMOTT, Mark R. - Mucosal Immunity, Vaccine Development
McKay, Derek - Neuroimmune regulation of gut function and elucidation of the active role of the epithelium in mucosal immunity.
Meyer, Ralph - malignant hematology
Mohialdin, Vian – Radiology; Anatomy
MOSSMAN, Karen - Virus Pathogenesis, Interferon, Immune Evasion, Signal Transduction, Tissue Culture, Gene Therapy, Cancer Therapy, Oncolytic Viruses
Nowaczyk, Malgorzata - Smith-Lemli-Opitz Syndrome
Ofosu, Frederick - Platelet Responses to Thrombin
Pennie, Ross - Use and abuse of antibiotics in outpatient practice; Diagnosis and management of acute otitis media in children.
Perdue, Mary - Physiology and pathophysiology of the small intestine and colon, examining the complex interaction between immune cells, nerves and epithelium that regulate mucosal function in health and result in dysfunction during disease
Potter, Murray - inborn errors of metabolism
Powers, Peter - diagnosis, prevention and treatment of venous thromboembolism.
Provias, John - neuro-oncology/angiogenesis
Radhi, Jasim - Anatomic Pathology; Gastrointestinal and Pancreatic tumors.
Ramsay, Jennifer – Pediatric and placental pathology; Dermatopathology; Gastrointestinal pathology; Endocrine pathology
RICHARDS, Carl D. - Inflammation, Arthritis, Synovium, Cytokines, Matrix Metalloproteinases, Adenovirus
Rosenfeld, Jack - Bio-analytical chemistry
ROSENTHAL, Kenneth L. - Mucosal Immunity, Mucosal Vaccination, Recombinant Adenovirus Vectors, CpG DNA, Herpes Simplex Virus (HSV), Human Immunodeficiency Virus (HIV), Cytotoxic T Lymphocyte (CTL), Chemokines
Shaughnessy, Stephen - Effects of anticoagulants on bone morphology and metabolism
Sheffield, William - Natural and recombinant coagulation proteins that either stimulate or suppress coagulation.
Sheardown, Heather - To develop polymeric biomaterials that interact with the cells and tissues of the surrounding biological environment and to characterize both the materials and the biological environment.
Singal, Dharam - Major histocompatibility complex, HLA, in man
Singh, Gurmit - Experimental Cancer Therapy for breast and prostate cancer; Mitochondria as a target for cancer chemotherapy; Strategies to modulate bone metastasis; Molecular and cellular mechanisms of photodynamic therapy
SMAILL, Fiona - HIV Infection, Infectious Diseases, Diagnostic Microbiology, Meta-Analyses, Pregnancy
Smieja, Marek - interaction between infections, inflammation, and chronic cardiovascular and respiratory diseases
SNIDER, Denis P. - Mucosal Immunity, T Cell Activation, Dendritic cell, Inflammation, graft-versus-host reaction (GVHR)
Srigley, John - pathology of tumours of the genitourinary tract including those of the prostate gland, urinary bladder, kidney and testis.
STÄMPFLI, Martin R. - COPD, Asthma, Immunology, Tolerance, Experimental Research
Sur, Monalisa - Neuropathology and Hematopathology.
Trus, Michael - investigating the role of aberrant gene expression in the pathogenesis acute myelogenous leukemia and therapeutic measures that restore normal gene expression in this disease.
Walsh Jennifer - Anatomic Pathology, Gynecological and Non-gynecological Cytology, Hematology and Autopsy
WAN, Yonghong - Dendritic Cells, Tumor Immunology, Cancer Vaccines, T Cells, Gene Therapy, Genetic Immunization, Adenovirus
Wang, Jack - Genotype-phenotype correlation study in cytogenetic rearrangements such as deletion, duplication, inverted duplication
Warkentin, Theodore – To characterize the pathophysiology, frequency, clinical presentation, diagnostic testing and treatment of heparin-induced thrombocytopenia; To characterize the pathophysiology, frequency, clinical presentation, diagnostic testing, and treatment of bleeding gastrointestinal angiodysplasia associated with cardiovascular disease
Waye, John – The study of human genetic disease, particularly the relationship between genotype and phenotype; Forensic identity testing.
West-Mays, Judith - Molecular and Genetic Mechanisms Regulating Eye Development and Disease
Whyte, Peter - Tumor suppressor genes and cell cycle regulation
XING, Zhou - Host Defense, T Cells, Macrophages, Cytokines, Mycobacteria, Pneumonia, Gene Transfer, Vaccines
Yang, Pinchang - Relationship of allergic reactions and inflammation in the intestinal mucosa, that involves brain and gut interaction, intestinal mucosa immune regulation, allergic mediators signal transduction and protein regulatory mechanisms, antigen transepithelial transportation and intestinal epithelial barrier functions
Young, Edward – Hemostasis and thrombosis, anticoagulants; Biological effects of heparin and related molecules; Extensive use of biochemical techniques such as gel and affinity chromatography; gel eletrophoresis; coagulation assays; uses of radiolabeled tracers; small animal and cell culture models.
Younglai, Edward - Identification of environmental pollutants in human reproductive fluids and the effects of similar mixtures on developmental reproductive processes.
Zhang, C - molecular biology and pathogenesis of human viral pathogens
Financial Support Available
McMaster University provides four types of financial support to full-time students.
- teaching assistantships
- graduate scholarships
- endowed scholarships
Teaching assistantships are provided to many graduate students offered admission to regular full-time programs. Duties vary according to department but will usually consists of tutorials, lab demonstrations and marking. The University provides graduate scholarship awards to most full-time graduate students in Ph.D. programs and in some Master's programs. Such scholarships are awarded annually based upon academic merit. A Ph.D. student is normally funded for four years. Students in Master's programs are usually supported for their first three to six terms depending on the department.
The endowed scholarships and bursaries have various conditions and amounts attached to them. All incoming students and currently enrolled students are automatically eligible and considered for all four types of financial assistance subject to the above eligibility conditions.
McMaster University has adopted a policy of ensuring that all full-time Ph.D. students earn at least $17,500 per year. Many programs have support levels in excess of this amount.
Admissions and Enquiries
Department of Pathology & Molecular Medicine
1200 Main Street West
Hamilton, Ontario L8N 3Z5