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STUDENTS  ::  Studying Microbiology in Canada

Studying Microbiology in Canada

McMaster University


Department Molecular Immunology, Virology & Inflammation


Overview The Molecular Immunology, Virology and Inflammation (MIVI) department includes many highly interactive laboratories with complementary interests. Research within this program is relevant to a number of serious diseases with an emphasis on the basic mechanisms and treatment of chronic inflammatory conditions (including asthma, fibrosis, inflammatory bowel disease, and rheumatic disease), infectious diseases (including HIV, chlamydia, human papilloma virus, tuberculosis), as well as treatment of cancer through modulation of immunity. Current research areas include:

- immunology and disease pathogenesis at mucosal surfaces including the airways, gastrointestinal and reproductive tracts
- examination of T-cell and antibody responses, cytokine cascades in inflammation and immunity
- investigation and development of vaccines and novel strategies of immuno-modulation and gene therapy
- immune stimulation for treatment of cancer
- roles of (and interactions between) lymphocytes, mast cells, eosinophils, macrophages, muscle function, nerve cells
- immunology of pregnancy, immunogenetics and HIV immunodeficiency



Research Facilities The research laboratories in the Health Sciences Centre at McMaster are well-supported and augmented by those in associated institutions located in Hamilton, e.g. the Hamilton Civic Hospitals Research Centre, the Father Sean O'Sullivan Research Centre and the Hamilton Regional Cancer Centre.

The MIVI program area includes laboratories which use the full range of molecular, in vitroand in vivoapproaches to examine disease related issues of importance to our understanding of basic mechanisms and the potential for new approaches to therapy. Close collaborations have been formed involving scientists of the Centre for Gene Therapeutics, the Intestinal Disease Research Program, the Rheumatic Disease Unit and the Asthma Research Groups as well as colleagues at other universities, research institutes and the pharmaceutical industry. A number of well-equipped on-campus facilities are available for use including the:

- Central facility of the Institute for Molecular Biology which provides important services to faculty using molecular biological techniques, including oligonucleotide and peptide synthesis and automated DNA sequencing
- Central Animal Facility
- Central Analytical Facility
- Occupational & Environmental Health Laboratory
- Electron Microscope (and Confocal Light Microscope) Facility
- Computer Services Unit.
- Health Sciences Library



List of Faculty ASHKAR, Ali A. - Innate Immunity, NK/NKT cells, IL-15, Mucosal Immunity, Toll-like Receptors, dsRNA, Tumor, Stem Cell Transplantation

BIENENSTOCK, John - Mast Cells, Neuro-Immune, Mucosal Immunity, Probiotics, Behaviour

BRAMSON, Jonathan - T lymphocyte, Genetic Vaccine, Gene Therapy, Virus, Cancer, Flow Cytometry

CHERNESKY, Max A. - Rapid Diagnosis, Infections, Immunization, Methods, Mechanisms, Pathogenesis, Laboratory

CLARK, David A. - Pregnancy Immunology, Tolerance, Cytokines, Transfusion immunomodulation, CD200, fgl2

COLLINS, Stephen M. - Inflammation, Nerves, Bacteria, Gastrointestinal Disease, Neuroimmunology, Probiotics

COX, Gerard P. - Pulmonary Inflammation, Neutrophil, Eosinophil, Apoptosis, Cell Biology

CROITORU, Kenneth - Mucosal Immunology, T Cells, T Cell Receptor, Inflammatory Bowel Disease, Crohn's Disease, Helicobacter Pylori, Host Resistance, Autoimmunity

DENBURG, Judah A. - Eosinophils, Basophils, Hemopoiesis, Allergic Inflammation, Allergic Disease, Autoimmune Disease, Psychoneuroimmunology

FOLEY, Ronan S. - Gene Transfer, Dendritic Cells, Adenoviral Gene Transfer, Cytokines, Stem Cells, Clinical Trials

FOX-ROBICHAUD, Alison - Inflammation, Sepsis, Liver, Endothelium, Adhesion molecules, Cytokines, Oxidative Stress

GAULDIE, Jack - Cytokine and Dendritic Cells, Inflammation and Immunity, Fibrosis, Tumour Immunotherapy, Interleukin-6, Gene Therapy

HARNISH, Delsworth G. - HPV, Molecular Biology, Education

JORDANA, Manel - Allergic Inflammation, Asthma, Peanut-induced Anaphylaxis, Immune Regulation, Cytokines, Chemokines, Co-stimulatory Molecule

KAUSHIC, Charu - Mucosal Immunology, Female Genital Tract, Sexually Transmitted Diseases, Sex Hormones, HIV, Vaccines

KHAN, Waliul - Mucosal Immunity, Host Defense, T Cells, Cytokines, Chemokines, Enteroendocrine Cells, Goblet Cells, Enteric Infection, Inflammation

KOLB, Martin - Lung Fibrosis,Tissue Repair, GeneTherapy, Small Animal Imaging, Drug Trials, Clinical Research

LICHTY, Brian - Vesicular Stomatitis Virus, Coronavirus, Cancer, Myeloma, Interferon

MACPHERSON, Andrew - Mucosal Immunology, Commensal Intestinal Bacterial, Inflammatory Bowel Disease, IgA, Dendritic Cells

MAHONY, James B. - Infectious Diseases, Chlamydia Pneumoniae, Virology, Atherosclerosis, Pathophysiology, Gene Expression, SARS, West Nile Virus

MARGETTS, Peter J. - Adenovirus, Fibrosis, Angiogenesis, Gene Therapy, Laser Capture Microdissection, Gene Regulation, Renal Disease, Peritoneal Dialysis

McDERMOTT, Mark R. - Mucosal Immunity, Vaccine Development

MOSSMAN, Karen - Virus Pathogenesis, Interferon, Immune Evasion, Signal Transduction, Tissue Culture, Gene Therapy, Cancer Therapy, Oncolytic Viruses

RICHARDS, Carl D. - Inflammation, Arthritis, Synovium, Cytokines, Matrix Metalloproteinases, Adenovirus

ROSENTHAL, Kenneth L. - Mucosal Immunity, Mucosal Vaccination, Recombinant Adenovirus Vectors, CpG DNA, Herpes Simplex Virus (HSV), Human Immunodeficiency Virus (HIV), Cytotoxic T Lymphocyte (CTL), Chemokines
SEHMI, Roma - Asthma Pathology, Allergic Inflammation, Tissue Eosinophilia, Eosinophilia, Eosinophil Progenitor Cells, Hemopoiesis, Cell Migration and Traffic, Bone Marrow, Eosinophils

SMAILL, Fiona - HIV Infection, Infectious Diseases, Diagnostic Microbiology, Meta-Analyses, Pregnancy

SNIDER, Denis P. - Mucosal Immunity, T Cell Activation, Dendritic cell, Inflammation, graft-versus-host reaction (GVHR)

STÄMPFLI, Martin R. - COPD, Asthma, Immunology, Tolerance, Experimental Research

WAN, Yonghong - Dendritic Cells, Tumor Immunology, Cancer Vaccines, T Cells, Gene Therapy, Genetic Immunization, Adenovirus

XING, Zhou - Host Defense, T Cells, Macrophages, Cytokines, Mycobacteria, Pneumonia, Gene Transfer, Vaccines


Financial Support Available McMaster University provides four types of financial support to full-time students.

- teaching assistantships
- graduate scholarships
- endowed scholarships
- bursaries.

Teaching assistantships are provided to many graduate students offered admission to regular full-time programs. Duties vary according to department but will usually consists of tutorials, lab demonstrations and marking. The University provides graduate scholarship awards to most full-time graduate students in Ph.D. programs and in some Master's programs. Such scholarships are awarded annually based upon academic merit. A Ph.D. student is normally funded for four years. Students in Master's programs are usually supported for their first three to six terms depending on the department.
The endowed scholarships and bursaries have various conditions and amounts attached to them. All incoming students and currently enrolled students are automatically eligible and considered for all four types of financial assistance subject to the above eligibility conditions.

McMaster University has adopted a policy of ensuring that all full-time Ph.D. students earn at least $17,500 per year. Many programs have support levels in excess of this amount.



Admissions and Enquiries Department of Molecular Immunology, Virology & Inflammation
Department of Molecular Immunology, Virology & Inflammation
McMaster University
Faculty of Health Sciences
Health Sciences Centre, Room 3N10
1200 Main Street West
Hamilton, Ontario L8N 3Z5

Phone: 905-525-9140
Fax: 905-546-1129
Email: askhsgp@mcmaster.ca

Web: http://www.fhs.mcmaster.ca/grad/medsci/research/mivi.htm


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